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Cold chain, and why it matters more than you think

What happens to a peptide in a hot mailbox, and how to store a library properly at home.

5 min read

Peptides degrade through hydrolysis, oxidation, and aggregation. Each of those processes accelerates with heat and moisture, which is why storage is not a footnote.

Lyophilized powder tolerates ambient shipping temperatures far better than solution. That is precisely why compounds ship as powder.

At rest, a dedicated refrigerator shelf away from the door is the simplest meaningful upgrade most people can make. Temperature stability matters more than the exact number.

For long horizons, a freezer at minus twenty preserves lyophilized material well. Avoid repeated freeze-thaw cycles; decant into aliquots instead.

All products referenced are sold for laboratory research use only and are not intended for human or veterinary use.

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