Long-acting amylin analogue for weight management
The Lancet · 2021
A phase 2 trial of a once-weekly amylin analogue reported dose-dependent weight reduction relative to placebo, with effects attributed to satiety and gastric emptying signalling.
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A long-acting amylin analogue studied alongside incretin compounds in satiety and metabolic research models.
From the literature
The Lancet · 2021
A phase 2 trial of a once-weekly amylin analogue reported dose-dependent weight reduction relative to placebo, with effects attributed to satiety and gastric emptying signalling.
Nature Metabolism · 2023
Combination research shows amylin receptor agonism acts through a receptor complex separate from GLP-1, producing additive effects on food intake in preclinical and early clinical models.
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